Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1051 | Male Reproduction | ICEECE2012

Ten years of EAA/EMQN quality control scheme for microdeletions of the Y chromosome

Tuttelmann F. , Hoefsloot L. , Patton S. , Simoni M. , Krausz C.

Introduction: Y-chromosomal azoospermia factor (AZF) microdeletions are one of the few well-established genetic causes of male infertility, specifically azoospermia or severe oligozoospermia. Since the introduction of a PCR-based method to easily detect the distinct deletion patterns, the screening of infertile men for Y microdeletions has become a very common genetic test performed frequently by a large number of laboratories. An external quality control scheme was establishe...